Cardiac research

Much of medical research has focused on the ‘bikini approach‘ to women’s health: breasts and reproductive organs. And the University of Toronto’s Dr. Wendy Tsang’s studies on heart research has found that, although women comprise 53% of patients with cardiovascular disease, in clinical trials they represented only:

  • 29% of subjects with coronary artery disease
  • 25% with congestive heart disease
  • 34% with cardiac arrhythmias

We need to change that. Women MUST get involved in cardiac research if we are to see improvements in diagnostics and treatment of our heart disease.

Before 1993, studies that tested new drugs had special eligibility criteria that prohibited women from participating. Those criteria have been dropped and all women are now eligible to participate in studies.

We do not know why heart disease kills more women over 50 years old than men of the same age. Almost nothing is known about this because, until recently, almost all research was done using men as subjects.

This is now beginning to change, and a woman can help researchers find out more, if not for herself, then for her mother, her sisters, her friends and especially for her daughters.

As Dr. Nieca Goldberg writes:

“When it comes to heart disease, women are not just small men.”

Examples of women’s heart disease studies in North America that are now recruiting:

  • Young women (19-55 years of age) with non-obstructive coronary artery disease: Prospective Registry of Young Women With Myocardial Infarction: Evaluating the Prevalence and Longterm Impact of Non-Atherosclerotic CAD (PRYME)
  • Women with early breast cancer: Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research (MANTICORE)
  • Women with severe symptomatic aortic stenosis who are eligible for Transcatheter Aortic Valve Implantation (TAVI). Women’s International Transcatheter Aortic Valve Implantation Registry (WINTAVI)
  • Women with past history of coronary artery disease and Type 2 diabetes/metabolic syndrome: Cardiovascular Inflammation Reduction Trial (CIRT)

Visit for more information about current research studies, or in Canada visit this Clinical Trials Database.

Please consider participating in heart research.


See also:  Are Women Being Left Behind in Cardiac Research? and Cardiac Research: Where Did All The Women Go?

4 Responses to “Cardiac research”

  1. Denise Barham June 24, 2013 at 4:25 pm #

    I believe women are left out of heart disease studies, etc. because: 1) Most heart doctors and research specialists are men and 2) Women are ignored when we finally do see a cardiologist or go to the ER.

    I know I have been (in both cases)! I think I’ll faint when, and if, I’m finally diagnosed! I know I have unstable angina, and am on meds but everyone keeps saying I’m too young, etc. (I’m 52)! Very frustrating.


    • Carolyn Thomas June 24, 2013 at 6:56 pm #

      Hi Denise – Frustrating indeed! Women are under-represented in cardiac research for so many reasons. For example, we are asked to participate less often than males are. And although women do volunteer to participate in hormone or breast cancer research trials, we are not volunteering to participate in cardiac research. It’s not just men who don’t think of heart disease as a women’s problem!


  2. Kathleen August 20, 2012 at 1:21 pm #

    I want to be part of a study on apical hypertrophic cardiomyopathy, but so far haven’t found one. In fact, as of now I have found only one published study that involved sizable numbers (about 100) and that is cited in journal articles, along with single case descriptions and a very few studies that involved much lower numbers (about 11-20). One letter in reply to an article pointed out problems with that article’s analysis and conclusions drawn from existing studies, and was a plea for more published information, even case studies, as there is very little data. Let’s call it Rare Condition Research Syndrome.


    • Carolyn Thomas August 20, 2012 at 5:25 pm #

      Hi Kathleen – that’s the trouble with rare diseases: there simply aren’t lots of people to either include in studies, or to benefit from studies’ conclusions (relative to non-rare disease) Have you checked out the NIH Office of Rare Disease Resources yet?


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