What I wish I knew back then: “Did my family history of heart disease lead to my heart attack?”

by Carolyn Thomas    ♥    @HeartSisters

A young 30-something in one of my Heart-Smart Women presentation audiences asked an intriguing question while we were discussing women’s cardiac risk factors.  She was worried about her own risk for developing heart disease one day because of her family history.  Her mother, she explained, had died several years earlier from a heart attack while only in her 40s. But then this young woman added a few additional facts about her Mum.  For example, her mother had also:

  • been significantly overweight
  • rarely exercised
  • lived with poorly managed Type 2 diabetes
  • been a heavy smoker for over two decades

This young woman, however, shared none of those risk factors.  Should she still be concerned about this family history of heart disease?   

The World Heart Federation helps to answer this question by reminding us:

“You can protect yourself by taking care of your heart, as the development of cardiovascular disease involves many different risk factors, not just your family history.

“We know that people often behave and act as their parents and siblings do. As a result, the genes and habits that cause us to be sedentary, to smoke, to be overweight/obese, or to follow poor diets often tend to cluster in families.”

It’s important to remember that not everybody who has a strong family history of cardiovascular disease will develop a cardiac event, and not everybody with cardiovascular disease has a family history at all. Mayo Clinic cardiologists add:

“ A family history of heart disease can increase your own risk, especially if a parent or sibling developed it at an early age (before age 55 for a close male relative such as your brother or father, and before age 65 for a close female relative such as your mother or sister).”

And if both parents were diagnosed with heart disease before the age of 55, your risk of developing heart disease can rise significantly compared to the general population.

Meanwhile, Dr. Rosalyn Carson-DeWitt suggests that you learn about ANY conditions your closest relatives have experienced that may be related to heart disease. This includes not only actual heart attacks, but angina (chest pain), strokes, high blood pressure, high cholesterol, obesity or diabetes.  If your parents or siblings had these conditions, you may be more likely to develop them, too.
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Keep in mind that the most important relatives to consider are those called “first degree”  (that is, only your parents and siblings).  In fact, a Johns Hopkins University study demonstrated that your siblings’ health history may be even more important than your parents’. People whose siblings have a history of heart disease carry a much greater likelihood of developing heart disease than if only their parents had the condition.(1)  
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I’ve heard women say that they know they have a family history of heart disease because their grandparent or uncle or cousin had a heart attack (often in old age) – but there is actually little evidence that the cardiac history of those who are not your first degree relatives (or who have cardiac diagnoses when they’re already elderly)  will impact your own cardiac risk.
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A stroke is also a type of cardiovascular disease (affecting blood flow to the brain instead of to the heart). Canada’s Heart and Stroke Foundation warns that you may be at higher stroke risk if a close family member (again, a parent or sibling) had a stroke before age 65 – and particularly if you are a woman whose mother has suffered a stroke.

Some heart rhythm disorders can also run in families. Alicia Burns, founder of Brugada Girl™, experienced distressing cardiac symptoms for 14 years that were misdiagnosed or dismissed entirely before finally being correctly diagnosed as Brugada Syndrome. Her Dad had died suddenly of cardiac arrest at age 55 (now believed to have also been caused by Brugada). Her whole family also knew that her Dad’s mother had lived with frequent fainting spells – one of the most common symptoms of Brugada. Yet it was only after her own diagnosis at age 34 that Alicia’s father/grandmother’s experiences began to make sense. Alicia finally had a cardiac defibrillator implanted in her heart to help prevent sudden cardiac arrest. A busy mother of seven, Alicia takes all of her children for regular cardiac testing.

Some heart valve disorders can also be inherited. A study in Denmark reported that the risk of aortic stenosis (one of the most common heart valve diseases in the elderly) doubles when a first degree relative also had the disease. This study also found that aortic stenosis risk increased by eight-fold in patients who have both heart disease and a family history. (2)

The risk for heart disease can increase even more when heredity is combined with lifestyle choices such as smoking, inactivity and/or eating an unhealthy diet.
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I had absolutely no family history of early heart disease when I survived a misdiagnosed “widowmaker” heart attack in 2008.
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But I have two brothers, two sisters and two children who, since my heart attack, have been quite cranky with me – because they now each have a family history of heart disease because of my diagnosis!
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(1)  Thanassoulis G, et al. Genetic associations with valvular calcification and aortic stenosis. N Engl J Med. 2013;368(6):503-512.
(2) Khurram, Nasir, et al. Coronary Artery Calcification and Family History of Premature Coronary Heart Disease. Circulation. 110(2004): 2150-56.

“What I Wish I Knew Back Then”  is a back-to-basics summer series of posts here on Heart Sisters that will revisit some of the most frequently asked questions from new heart patients. You can find more of these posts here.

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NOTE FROM CAROLYN:   I wrote more about family history of early heart disease and other cardiac risk factors in my book, A Woman’s Guide to Living with Heart Disease”. You can ask for it at your local library or favourite bookshop (please support your neighbourhood independent booksellers!) or order it online (paperback, hardcover or e-book) at Amazon – or order it directly from my publisher, Johns Hopkins University Press (use their code HTWN to save 30% off the list price).

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 Q:  Has a family history of cardiovascular disease affected your own health?

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See also:

The cure myth

Heart attack: did you bring this on yourself?

When the ‘wrong’ family member gets heart disease

4 thoughts on “What I wish I knew back then: “Did my family history of heart disease lead to my heart attack?”

  1. Hi Carolyn,

    I’m fascinated by “secrets” in our genes. All kinds.

    “It’s important to remember that not everybody who has a strong family history of cardiovascular disease will develop a cardiac event, and not everybody with cardiovascular disease has a family history at all.”

    Gosh, I could insert breast cancer in there in place of cardiovascular disease and cardiac event. So far, I’m the only sibling in my family to be diagnosed. And so far, all my kids, nieces, and nephews are okay too. Thank God. I try not to overthink all the potential risks and possibilities or I could drive myself (and them) a little nuts.

    I’m sure it’s unsettling at times that your siblings and kids now need to check yes in that family history box for heart disease.

    Interesting topic. Thank you for writing about it. Stay well and take care.

    Liked by 1 person

    1. Hello Nancy! This is so true of so many potential diagnoses, isn’t it? We MIGHT have inherited a culprit gene from our family – or we might NOT. It’s a crapshoot. I too believe it’s important to avoid overthinking risks and possibilities (I like how the late Yale professor Dr. Susan Nolen-Hoeksema wrote about what she calls RUMINATING – very tempting of course, especially when first diagnosed – no matter the diagnosis!) For example, she writes:

      “When people ruminate about problems, they remember more negative things that have happened to them in the past, they interpret situations in their current lives more negatively, and they are more hopeless about the future…”

      I could ruminate (based on what science tells us: that the #1 risk factor for a heart attack is having already had one!) But the reality is that I could get flattened by a wayward bus tomorrow for all I know – yet I spend zero time worrying about every bus I see.

      Take care, Nancy – stay cool out there. . . ♥

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  2. Hi Susan – your situation is interesting, because there’s really no way of knowing for sure if you had your triple bypass surgery as a result of your cardiac family history (e.g. both parents diagnosed at relatively young ages) or as a result of 40 years of smoking. Maybe a little of both?

    I hope you are doing well now.
    Take good care. . . ♥

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  3. Hello Carolyn
    I would have to say yes to family history. My dad had a heart attack while my mom and him were on vacation. He had my mom drive him home to go to our local hospital. He was 56 yrs old and had a triple bypass. My mom had stents. I think she had 2 she was early 60’s. I had triple bypass at 59. The only difference is I did not have a heart attack. But I will not blame them completely – I did spend about 40 yrs smoking.

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